Biological Anthropology deals with the comparative biogenetics of man. Human Variation can be measured at both the individual level and at the population level and the polymorphism of genetic marker traits a number of interesting dynamic effects are observed through the selective effects of the genotypes. But, source-sink structures that are known to occur in spatially structured models can be seen in the genetic model if one of the genotypes is under selective elimination. The selective effects on genotypes could generally be perceived by its manifestation in prezygotic and postzygotic stages, which is further extendable to neonatal and postnatal periods in human. Actual studies on the products of conception, living, or dead (aborted material) of these couples essential for understanding of process of selective elimination of the alleles. In 80 of the 124 chromosome-analyzed aborted foeti, the ABO blood groups and Haptoglobin (HP) were determined by the mixed cell agglutinating reaction and PAGE. The results of the ABO blood group and HP were compared with 100 newborns along with their parents (181) from the same area. Among the abortuses along with their parents with normal karyotype, a significant (p <0.05) association of higher ABO incompatible couple combination, significantly higher (p<0.05) A alleles and as well as significantly (P <0.05) excess frequency of HP*1 allele among the aborted fetus has been noticed in comparison to the newborn. Thus, the present study envisaged HP*1 allele is an additional risk factor for early spontaneous abortions together with ABO incompatibility between the couples