| 个人简介 | |
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 Prof. Jeanne Adiwinata Pawitan Universitas Indonesia, Jakarta, Indonesia |
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| 标题： Organ derived scaffold for tissue engineering | |
| 摘要： Some diseases may cause organ damage that may lead to death, except a successful organ transplant can replace the function of the damaged organ. However, there is usually shortage in supply of organs to be transplanted. Therefore, tissue engineering is a new hope to develop organs for transplantation, or organoids that may help the patients to survive for a while, as a bridging therapy before a suitable organ is available. Tissue engineering methods have been used to develop organs or organoids. These methods are variable, from using pluripotent stem cells, progenitor cells, combination of various cells, or combination of cells and scaffold in a suitable environment. The use of scaffold in tissue engineering may promote the cells that are seeded on to the scaffold to develop into the desired organ or organoid. To avoid rejection, the cells to be seeded onto the scaffold can be patient derived cells. Various scaffolds have been used in various studies. The best is organ derived scaffold that has the natural structure of organ matrix, including the matrix for developing blood vessels that may keep the developed organ or organoid to remain viable. The aim of this speech is to highlight the various ways to develop a natural organ derived scaffold by using combination of various substances, which eliminate the cells, and techniques to immerse the substances to the whole of the natural organ to eliminate the cells. | |
| 简介： Prof. dr. Jeanne Adiwinata Pawitan, PhD has been Graduated from the Faculty of Medicine, Universitas Indonesia (FMUI) as Medical Doctor, and Master in Medical Biology, and started working at the Department of Histology FMUI. Later on she obtained her PhD from Osaka University, Osaka, Japan, continued working at the Department of Histology FMUI, and was appointed as Professor in 2005. Presently, besides serving as Professor in the Department of Histology, Faculty of Medicine Universitas Indonesia (FMUI), Jakarta, Indonesia, she also works at Stem Cell Medical Technology Integrated Service Unit, RSCM - FMUI as quality control chief officer, and at Stem Cell and Tissue Engineering Research Center, Indonesia Medical Education and Research Institute (IMERI), FMUI as lab manager. Her research interests and projects are in stem cell and regenerative medicine, and she published various research papers mainly in the isolation, culture, characterization, differentiation and production of mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord. Recently her newest project is liver organoid culture, liver derived natural scaffold, differentiation of fibroblast into hepatocyes using transcription factors, and translational use of MSCs in various diseases/conditions. In addition she is active in writing review articles and systematic reviews concerning production method and usage of stem cells in regenerative medicine, and recently concerning COVID-19. | |
