Sandeep Sachdeva_IPC-BT 2019

Biography
Dr. Sandeep Sachdeva Feroz Specialist Hospital, India
Title: VITAMIN D DEFICIENCY AND CHILDHOOD RESPIRATORY MORBIDITY: A PROSPECTIVE RANDOMISED CONTROLLED STUDY
Abstract: Background: Vitamin D is known to bear protective effect in prevention and therapy of several childhood systemic morbidities. With a null hypothesis of the positive impact of vitamin D supplementation among children with Recurrent Respiratory Infections (RRIs) and chronic cough, the present study was planned especially in view of the fact that not many similar studies, systematic reviews or meta analyses have been effected towards this pursuit. Methods: A total of 104 children aged between 6 months and 14 years presenting to the Paediatric Out patient department with Recurrent respiratory infections and chronic cough were recruited for this hospital based prospective interventional study planned over a duration of 2 years (2016-2018). Vitamin D assay was done in all the candidate children and those with deficient/insufficient levels were given appropriate oral supplementation. Further, these children were followed at 3 monthly intervals up to a duration of 12 months for change in respiratory symptomatology , particularly with a view towards reduction in episodes/severity of chest infections and attainment of linear growth. Results: A total of 104 patients were analysed, of whom 44 patients had a diagnosis of RRI and 60 patients were in the Chronic cough group. Serum Vitamin D levels were found to be low in 64% of patients with RRI and 70% of chronic cough patients. There was a statististically significant decline in the number of episodes of RRI and Chronic cough after supplementation (p<0.05). In the RRI category, none of the children had enough recurrences to be labelled as RRI after Vitamin D supplementation when followed upto 12 months.In chronic cough patients belonging to Vitamin D deficient subgroup as well, there was a statistically significant decline in the recurrence of cough during a follow up of 12 months(p<0.05). Conclusion: RRIs and Chronic cough along with hypovitaminosis D are significant preventable public health problems in paediatric population . Majority of patients of RRI and Chronic cough have Vitamin D deficiency. Screening for vitamin D among ‘at risk’ children and subsequent supplementation thereof even in children with specific etiology cough can go a long way towards mitigating mortality and morbidity due to respiratory illnesses in children.

Biography

Dr. Sandeep Sachdeva
Feroz Specialist Hospital, India

Title: VITAMIN D DEFICIENCY AND CHILDHOOD RESPIRATORY MORBIDITY: A PROSPECTIVE RANDOMISED CONTROLLED STUDY

Abstract:

Background: Vitamin D is known to bear protective effect in prevention and therapy of several childhood systemic morbidities. With a null hypothesis of the positive impact of vitamin D supplementation among children with Recurrent Respiratory Infections (RRIs) and chronic cough, the present study was planned especially in view of the fact that not many similar studies, systematic reviews or meta analyses have been effected towards this pursuit. Methods: A total of 104 children aged between 6 months and 14 years presenting to the Paediatric Out patient department with Recurrent respiratory infections and chronic cough were recruited for this hospital based prospective interventional study planned over a duration of 2 years (2016-2018). Vitamin D assay was done in all the candidate children and those with deficient/insufficient levels were given appropriate oral supplementation. Further, these children were followed at 3 monthly intervals up to a duration of 12 months for change in respiratory symptomatology , particularly with a view towards reduction in episodes/severity of chest infections and attainment of linear growth.

Results: A total of 104 patients were analysed, of whom 44 patients had a diagnosis of RRI and 60 patients were in the Chronic cough group. Serum Vitamin D levels were found to be low in 64% of patients with RRI and 70% of chronic cough patients. There was a statististically significant decline in the number of episodes of RRI and Chronic cough after supplementation (p<0.05). In the RRI category, none of the children had enough recurrences to be labelled as RRI after Vitamin D supplementation when followed upto 12 months.In chronic cough patients belonging to Vitamin D deficient subgroup as well, there was a statistically significant decline in the recurrence of cough during a follow up of 12 months(p<0.05).

Conclusion: RRIs and Chronic cough along with hypovitaminosis D are significant preventable public health problems in paediatric population . Majority of patients of RRI and Chronic cough have Vitamin D deficiency. Screening for vitamin D among ‘at risk’ children and subsequent supplementation thereof even in children with specific etiology cough can go a long way towards mitigating mortality and morbidity due to respiratory illnesses in children.